Stimulation of the Utilization of 1-14C-Glucose in Chicken Red Blood Cells Infected with Plasmodium Gallinaceum *

Abstract
Summary Malaria-infected chicken erythrocytes exhibited a marked increase in the metabolism of 1-14C-glucose to 14CO2. Addition of the cofactors, TPN or ATP, to red cell and parasite total hemolysate usually accelerated CO2 production. Virtually all activity was confined to the supernatant fluid as compared to the stroma. A pentose phosphate pathway is apparently absent in Plasmodium gallinaceum, and the parasite apparently utilizes this pathway in the host erythrocyte.