THE 3RD CLASS OF NEW TUMOR PROMOTERS, POLYACETATES (DEBROMOAPLYSIATOXIN AND APLYSIATOXIN), CAN DIFFERENTIATE BIOLOGICAL ACTIONS RELEVANT TO TUMOR PROMOTERS
- 1 January 1982
- journal article
- research article
- Vol. 73 (3), 495-497
Abstract
Aplysiatoxin is a new class of potent tumor promoter and debromoaplysiatoxin may be a weak promoter. Aplysiatoxin and debromoaplysiatoxin showed the same potency on irritation of mouse ear and induction of ornithine decarboxylase activity on mouse skin, but debromoaplysiatoxin was much weaker than aplysiatoxin in induction of adhesion of [human promyelocytic leukemia] HL-60 cells.This publication has 5 references indexed in Scilit:
- Indole alkaloids: dihydroteleocidin B, teleocidin, and lyngbyatoxin A as members of a new class of tumor promoters.Proceedings of the National Academy of Sciences, 1981
- Teleocidin, lyngbyatoxin A and their hydrogenated derivatives, possible tumor promoters, induce terminal differentiation in HL-60 cellsCancer Letters, 1981
- Aggregation of human lymphoblastoid cells by tumor-promoting phorbol esters and dihydroteleocidin BBiochemical and Biophysical Research Communications, 1980
- A possible naturally occurring tumor promoter, teleocidin B from StreptomycesBiochemical and Biophysical Research Communications, 1979
- A New Toxic Substance, Teleocidin, Produced byStreptomycesAgricultural and Biological Chemistry, 1962