Interferon treatment inhibits glycosylation of a viral protein
- 1 October 1980
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 287 (5781), 454-456
- https://doi.org/10.1038/287454a0
Abstract
The effects of tunicamycin (TM) and IFN [interferon] in [mouse fibroblast] L cells are compared. Treatment with TM or IFN reduced the production of infectious VSV [vesicular stomatitis virus] particles, decreased the amount of G and M proteins in VSV released from treated cells, and inhibited an early step in the formation of asparagine-linked oligosaccharide chains, the incorporation by membrane preparations from treated cells of N-acetylglucosamine into glycolipids with the properties of dilichol derivatives.This publication has 27 references indexed in Scilit:
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