Iron (III) induces aggregation of hyperphosphorylated τ and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease
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Open Access
- 1 September 2002
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 82 (5), 1137-1147
- https://doi.org/10.1046/j.1471-4159.2002.t01-1-01061.x
Abstract
Iron as well as aluminum is reported to accumulate in neurons with neurofibrillary tangles (NFTs) of Alzheimer's disease (AD) brain. Previously we demonstrated that aluminum (III) shows phosphate‐dep...Keywords
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