The regulatory region of the biotin operon in Escherichia coli
- 1 December 1978
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 276 (5689), 689-694
- https://doi.org/10.1038/276689a0
Abstract
The biotin anabolic operon in E. coli is apparently transcribed divergently from 2 partially overlapping face-to-face promoters. A mutation that increases transcription in vivo creates an additional promoter in vitro. The putative operator contains an imperfect palindromic sequence that partially overlaps the promoters. The regulatory and genetic implications of these findings are discussed.Keywords
This publication has 49 references indexed in Scilit:
- Nucleotide sequence changes produced by mutations in the lac promoter of Escherichia coliJournal of Molecular Biology, 1977
- Nucleotide sequence of bacteriophage φX174 DNANature, 1977
- DNA base sequence of the po promoter region of phage λNature, 1977
- λ represser regulates the switch between PR and Prm promotersNature, 1976
- Regulation of the regulatory gene for the arabinose pathway, araCJournal of Molecular Biology, 1976
- Bacteriophage T7 early promoters: Nucleotide sequences of two RNA polymerase binding sitesJournal of Molecular Biology, 1975
- Operator and promoter mutations affecting divergent transcription in the bio gene cluster of Escherichia coliJournal of Molecular Biology, 1975
- Divergent transcription in the argECBH cluster of genes in Escherichia coli K12Journal of Molecular Biology, 1974
- Divergent orientation of transcription from the biotin locus of Escherichia coliJournal of Molecular Biology, 1971
- A two-dimensional fractionation procedure for radioactive nucleotidesJournal of Molecular Biology, 1965