A patient who entered the hospital with a fracture of the right leg, the result of a rather trivial injury, giving a history of previous fractures, likewise following slight trauma, was found, on roentgen-ray examination, to have a pathologic fracture as the result of a rather obscure bone condition which has been termed osteosclerosis fragilis generalisata, Marmorknochen (marble bone), or Albers-Schönberg disease. Inasmuch as only nine other cases of this disease have been reported, all of which have been in the foreign literature, none in the English language, the history of this case is given, together with the roentgen-ray study of the entire skeleton and a review of the literature of this subject to date. REPORT OF CASE History.—W. S., a schoolboy, aged 11 years, born in this country, was admitted to my service at the Cook County Hospital, April 20, 1922. He was brought to the hospital by