Effect of Partial Deficiency of Threonine on Enzyme Activity and Fat Deposition in Liver.

Abstract
The effect in the rat of a partial deficiency of threonine on the activities of several liver enzymes and on liver fat deposition has been detd. Liver fat deposition was higher in animals receiving the threonine-de-ficient diet. The activities of the mitochondrial enzymes, succinic oxidase and choline oxidase, were higher in liver homogenates from threonine-deficient animals. Endogenous respiration and the activities of the cytoplasmic enzymes, xanthine oxidase and tyrosine oxidase, were lower in the livers of animals fed diets deficient in threonine.