High Dose Cyclophosphamide as an Adjunct to Radiotherapy for Advanced Seminoma
- 1 May 1977
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Urology
- Vol. 117 (5), 613-614
- https://doi.org/10.1016/s0022-5347(17)58554-7
Abstract
Two patients with advanced seminoma of the testis were given single i.v. injections of high dose (1.5 and 2.0 g/m2) cyclophosphamide. Both patients experienced prompt, dramatic objective regressions without severe toxicity. Definitive radiotherapy, deemed technically unfeasible before cyclophosphamide administration, was administered subsequently. Long-term complete remissions (> 16 and 28 mo.) were attained in both patients. High dose cyclophosphamide may prove useful in selected patients with disseminated seminoma.This publication has 4 references indexed in Scilit:
- The chemotherapy of urologic cancerCancer, 1975
- Radiotherapy for Pure Seminoma of the TestisRadiology, 1975
- Treatment of Testicular CancerAnnual Review of Medicine, 1975
- High-dose cyclophosphamide therapy for malignant disease.Toxicity, tumor response, and the effects of stored autologous marrowCancer, 1972