Gastrointestinal Manifestations of Chronic Granulomatous Disease

Abstract

Four of nine patients with chronic granulomatous disease had gastrointestinal symptoms; in three of these perianal fistulas developed, and two had friable rectal mucosa. All four had vitamin B₁₂ malabsorption, and two had steatorrhea. In addition two asymptomatic patients had malabsorption of vitamin B₁₂.