The Pattern of Memory Loss Resulting From Intravenously Administered Diazepam
- 1 May 1979
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 36 (5), 296-300
- https://doi.org/10.1001/archneur.1979.00500410074011
Abstract
• A word recognition task was designed to determine the stage in memory affected by a single 10-mg intravenous injection of diazepam and the duration of the effect. Injection in three experimental subjects produced an anterograde amnesia for the 14 to 24-minute period immediately after injection. Memory loss resulted from impaired storage, the stage during which information is entered into memory. Retention and retrieval stages of memory were unaffected. This temporary amnesia may result from increased inhibition in the hippocampal system produced by diazepam, which shares many properties with the inhibitory neurotransmitter γ-aminobutyric acid.This publication has 15 references indexed in Scilit:
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