Messenger RNA Structure: Compatibility of Hairpin Loops with Protein Sequence
- 17 March 1972
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 175 (4027), 1264-1266
- https://doi.org/10.1126/science.175.4027.1264
Abstract
Examination of the amino acid sequences of human cytochrome c and the α-chain variant of human hemoglobin Constant Spring has revealed the possiblity for base-paired hairpin loops in the messenger RNA's for these proteins. A similar analysis of the bacteriophage R17 coat protein suggests an additional unobserved loop in the R17 RNA. If such loops are present in messenger RNA's generally, it would suggest that DNA has more than one stable base-paired conformation.Keywords
This publication has 12 references indexed in Scilit:
- Haemoglobin Constant Spring—A Chain Termination Mutant ?Nature, 1971
- Mapping of the lactose operatorJournal of Molecular Biology, 1971
- Prediction of RNA Secondary StructureProceedings of the National Academy of Sciences, 1971
- Non-Darwinian EvolutionScience, 1969
- Evolution of the genetic apparatusJournal of Molecular Biology, 1968
- The origin of the genetic codeJournal of Molecular Biology, 1968
- The sequence of 5 s ribosomal ribonucleic acidJournal of Molecular Biology, 1968
- Genetic variability maintained in a finite population due to mutational production of neutral and nearly neutral isoallelesGenetics Research, 1968
- Amino Acid Sequence Studies on the Tryptic Peptides of the Coat Protein of the Bacteriophage R17*Biochemistry, 1967
- Model for DNA and Protein Interactions and the Function of the OperatorNature, 1966