Hypoxanthine Dehydrogenase in the Developing Chick Embryonic Kidney
- 1 November 1962
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 111 (2), 340-343
- https://doi.org/10.3181/00379727-111-27785
Abstract
The activity of Hypoxanthine Dehydrogenase was determined in the meso- and metanephric renal tissue of the chick embryo and related to the amount of soluble protein in these tissues during successive developmental stages. The period of most rapid increase of specific activity occurred at 6-7 days in the meso-nephros and at 13-15 days in the metanephros. The highest specific activity was obtained on the 14th day in the mesonephric tissue which in the subsequent period of incubation exhibited decreasing hypoxanthine dehydrogenase activity. The metanephric tissue, which becomes the functional kidney of the adult attained a plateau of hypoxanthine dehydrogenase activity by the 16th day. The differentiation of the embryonic kidneys with respect to hypoxanthine dehydrogenase activity reported in these studies is well correlated with previous findings of renal function in the growing embryo studied by excretion of dyes by the renal tubules.Keywords
This publication has 3 references indexed in Scilit:
- A series of normal stages in the development of the chick embryoJournal of Morphology, 1951
- PURIFICATION OF THE HYPERGLYCEMIC-GLYCOGENOLYTIC FACTOR FROM INSULIN AND FROM GASTRIC MUCOSAJournal of Biological Chemistry, 1949
- Xanthine oxidase in the avian embryoBiochemical Journal, 1930