The Structure and Evolution of the HLA-Bw4 and Bw6 Antigens
- 11 December 2008
- journal article
- research article
- Published by Wiley in Tissue Antigens
- Vol. 13 (5), 334-341
- https://doi.org/10.1111/j.1399-0039.1979.tb00805.x
Abstract
The HLA-Bw4 and Bw6 antigenic determinants co-migrated with HLA-B determinants on gel-filtration, sucrose density gradient centrifugation and affinity chromatography, using Lens culinaris lectin and antibody against human .beta.2 microbulin. The HLA-Bw4 and Bw6 determinants apparently reside on the same polypeptide chain as other HLA-B locus determinants. The implications of this in terms of the evolution of cross reacting groups of antigens at the HLA-B locus were discussed.This publication has 14 references indexed in Scilit:
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