Abstract
To elucidate whether diminished pituitary gonadotropin reserve can be restored by repeated stimulation with luteinizing-hormone-releasing hormone, plasma luteinizing hormone and follicle-stimulating hormone responses were studied before and after daily intravenous infusion of 400 μg of luteinizing-hormone-releasing hormone for two to 23 days, in patients with hypogonadotropic hypogonadism of various causes.

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