CLINICAL STUDIES OF INDUCTION AGENTS X: THE EFFECT OF PHENOTHIAZINE PREMEDICATION ON THIOPENTONE ANAESTHESIA
Open Access
- 1 February 1964
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 36 (2), 106-109
- https://doi.org/10.1093/bja/36.2.106
Abstract
A standard operative procedure and anaesthetic technique were employed to study the effect of phenothiazine premedication on thiopentone anaesthesia. The premedicants were divided into three groups according to their analgesic action as found 60 to 90 minutes after intramuscular injection. Markedly antanalgesic drugs increase the incidence and severity of excitatory phenomena after thiopentone, but this effect is masked by the use of pethidine. Analgesic and slightly antanalgesic phenothiazines do not affect thiopentone anaesthesia.Keywords
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