Temporal Summation and Refractoriness in Hypothalamic Reward Neurons as Measured by Self-Stimulation Behavior
- 21 August 1970
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 169 (3947), 782-785
- https://doi.org/10.1126/science.169.3947.782
Abstract
A neurophysiological technique of double-pulse stimulation has been applied to freely moving rats with chronic indwelling electrodes in the hypothalamic reward area. Self-stimulation thresholds, measured as a function of the interpulse interval, generated curves with time constants characteristic of refractory periods and temporal synaptic summation. The results indicate a way of studying central neuronal processes for which the overt behavior of the animal is the dependent variable.Keywords
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