Chromosome aberration frequencies after partial-body irradiation of Syrian hamsters

Abstract

Graded X-ray doses up to 6.0 Gy were delivered to the rear 1/3 of body length (≃ 1/3 body mass) of Syrian hamsters and 24 h later, peripheral blood lymphocytes were sampled, set up in culture together with bromodeoxyuridine and first poststimulation mitotic cells were scored for chromosome-type aberrations. Very few aberrations were found at any dose and the response curve for centric exchanges (“dicentric + centric rings”) had no significant curvature or slope.