Canine Cyclic Neutropenia
Open Access
- 1 March 1974
- journal article
- Published by American Society for Clinical Investigation in JCI Insight
- Vol. 53 (3), 950-953
- https://doi.org/10.1172/jci107636
Abstract
Two normal collie dogs were given 1,200 R total body irradiation followed by successful marrow grafts from their grey collie littermates with cyclic hematopoiesis. During observation periods of 97 and 41 days after grafting, both previously normal recipients showed regular cyclic fluctuations of their granulocyte and reticulocyte counts similar to those observed in their donors. These findings suggest that canine cyclic neutropenia is due to a defect in the marrow stem cell.Keywords
This publication has 6 references indexed in Scilit:
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