Ketotifen in adult asthma.
- 9 February 1980
- Vol. 280 (6211), 360-361
- https://doi.org/10.1136/bmj.280.6211.360
Abstract
The efficacy and adverse effects of ketotifen 1 mg twice daily and 2 mg twice daily were compared with placebo in 50 patients with atopic asthma in a multicentre, double-blind study. Ketotifen in the higher dosage caused a slight reduction in salbutamol usage and a modest improvement in breathing in patients not already receiving inhaled corticosteroids. The drug was ineffective in patients receiving inhaled corticosteroids. Drowsiness was a troublesome effect causing withdrawal from treatment or reduction of dosage in seven patients while receiving ketotifen compared with only three while receiving placebo.Keywords
This publication has 6 references indexed in Scilit:
- A placebo‐controlled trial of ketotifen (HC 20‐511, Sandoz) in allergen induced asthma and comparison with disodium cromoglycateClinical and Experimental Allergy, 1979
- Clinical investigation of agents with prophylactic anti‐allergic effects in bronchial asthma*Clinical and Experimental Allergy, 1978
- Comparison between ketotifen and DSCG in bronchial challengeClinical and Experimental Allergy, 1978
- The pharmacological properties of a new, orally active antianaphylactic compound: ketotifen, a benzocycloheptathiophene.1978
- DISODIUM CROMOGLYCATE IN THE TREATMENT OF ALLERGIC BRONCHIAL ASTHMAThe Lancet, 1968
- A DOUBLE-BLIND TRIAL OF DISODIUM CROMOGLYCATE IN THE TREATMENT OF ALLERGIC BRONCHIAL ASTHMAThe Lancet, 1967