Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice
Top Cited Papers
- 1 October 2008
- journal article
- research article
- Published by Elsevier in Cancer Cell
- Vol. 14 (4), 312-323
- https://doi.org/10.1016/j.ccr.2008.09.001
Abstract
No abstract availableKeywords
This publication has 54 references indexed in Scilit:
- Discovery, In Vivo Activity, and Mechanism of Action of a Small-Molecule p53 ActivatorCancer Cell, 2008
- Negative regulation of the deacetylase SIRT1 by DBC1Nature, 2008
- NAD+-dependent deacetylation of H4 lysine 16 by class III HDACsOncogene, 2007
- Sirtuins: critical regulators at the crossroads between cancer and agingOncogene, 2007
- SIRT1 Regulates the Function of the Nijmegen Breakage Syndrome ProteinMolecular Cell, 2007
- SIRT1 promotes DNA repair activity and deacetylation of Ku70Experimental & Molecular Medicine, 2007
- Resveratrol improves health and survival of mice on a high-calorie dietNature, 2006
- Molecular Mechanism of the Recruitment of NBS1/hMRE11/hRAD50 Complex to DNA Double-strand Breaks: NBS1 Binds to γ-H2AX through FHA/BRCT DomainJournal of Radiation Research, 2004
- Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespanNature, 2003
- Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.Proceedings of the National Academy of Sciences, 1993