The sequence of four structural and two regulatory methionine genes in theSalmonella typhimuriumlinkage map
- 1 August 1968
- journal article
- research article
- Published by Hindawi Limited in Genetics Research
- Vol. 12 (3), 341-354
- https://doi.org/10.1017/s0016672300011927
Abstract
Three-point transduction analysis was employed to determine the sequence of four structural and two regulatory methionine genes (metA, B, F, H and metI, J, respectively) on two apparently adjacent transduction fragments in Salmonella typhimurium. These fragments were subsequently orientated with respect to each other and the rest of the linkage map by the analysis of recombinants obtained in conjugation experiments. The following clockwise sequence of genes is proposed: -metJ-metB-metF-argF-thi-purD-metA-metI-metH-. The bearing of these results on the regulation of the metB–F and metA–H clusters is discussed.Keywords
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