Degradation of Lipids in Yeast (Saccharomyces cerevisiae) at the Early Phase of Organic Solvent-induced Autolysis

Abstract

Initial stage of organic solvent-induced autolysis in yeast was studied with ¹⁴C-acetate labeled cells. In the case of toluene-induced autolysis, primary cell injury which was estimated by leakage of UV absorbing substances from cell accompanied rapid deacylation of phospholipids. Lysophospholipids did not occur during autolysis. When autolysis was induced by addition of ethyl acetate, phospholipids of yeast cells were not degraded so much. Ethyl acetate rather inhibited yeast phospholipase activity under the condition tested.