Bone collagen metabolism in vitamin D deficiency (Short Communication)
- 15 January 1973
- journal article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 132 (1), 113-115
- https://doi.org/10.1042/bj1320113
Abstract
Radioisotope studies have shown that collagen synthesized in the shafts of bones from rachitic rats and chicks is similar in chain composition to that normally synthesized. However, the extent of lysine hydroxylation in both α1- and α2-chains is increased, by approx. 15–30% in the rat and by 50% in the chick.Keywords
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