An open, noncomparative study of amoxapine in borderline disorders
- 1 January 1989
- journal article
- research article
- Published by Wiley in Acta Psychiatrica Scandinavica
- Vol. 79 (1), 89-93
- https://doi.org/10.1111/j.1600-0447.1989.tb09238.x
Abstract
Five patients with borderline personality disorder (BPD) and 5 patients with schizotypal personality disorder (SPD) completed at least 3 weeks of treatment with amoxapine. The patients fulfilled DSM‐III criteria for borderline disorders and scored 7 points or more in Gunderson's Diagnostic Interview for Borderlines (DIB). The final median medication in patients with BPD was 200 mg amoxapine/day and 42 mg oxazepam/day. Duration of treatment averaged 28 days. In patients with SPD the corresponding figures were 250 mg amoxapine/day, 36 mg oxazepam/day and 39 days. The study suggests that amoxapine improves schizophrenic‐like and depressive symptoms in patients with schizotypal personality disorders (SPD). No effect could be shown in patients with borderline personality disorders (BPD).Keywords
This publication has 28 references indexed in Scilit:
- Amoxapine elevates serum prolactin in depressed menJournal of Affective Disorders, 1983
- Ligand binding and platelet uptake studies of loxapine, amoxapine and their 8-hydroxylated derivativesJournal of Affective Disorders, 1982
- The effect of amoxapine and imipramine on serum prolactin levelsArchives of Internal Medicine, 1981
- The Schedule for Schizotypal Personalities (SSP): A diagnostic interview for schizotypal featuresPsychiatry Research, 1981
- Amoxapine versus amitriptyline in endogenous depression.Acta Psychiatrica Scandinavica, 1979
- The effects of 2-chloro-11-(4-methyl-l-piperazinyl)-dibenz[b,f] [1,4]oxazepine (loxapine) and its derivatives on the dopamine-sensitive adenylate cyclase of rat striatal homogenatesBrain Research, 1976
- Correlation of Subjective Side Effects with Plasma Concentrations of NortriptylineBMJ, 1970
- A RATING SCALE FOR EXTRAPYRAMIDAL SIDE EFFECTSActa Psychiatrica Scandinavica, 1970
- A RATING SCALE FOR DEPRESSIONJournal of Neurology, Neurosurgery & Psychiatry, 1960
- THE ASSESSMENT OF ANXIETY STATES BY RATINGPsychology and Psychotherapy: Theory, Research and Practice, 1959