Effect of pramlintide on satiety and food intake in obese subjects and subjects with type 2 diabetes

Abstract
Long-term trials in insulin-treated subjects with type 2 diabetes have shown that adjunctive treatment with the amylin analogue pramlintide reduces HbA1c levels and elicits weight loss. While amylin reduces food intake in rodents, pramlintide’s effect on satiety and food intake in humans has not yet been assessed.