MOUSE HYDROCEPHALUS AND ENCEPHALITIS FOLLOWING INTRACEREBRAL INFECTION WITH NEWCASTLE-DISEASE VACCINE VIRUSES
- 1 January 1976
- journal article
- research article
- Vol. 57 (4), 472-480
Abstract
Hydrocephalus and encephalitis in 14 day old mice was induced by an intracerebral inoculation of a high dose of live Newcastle disease vaccine viruses. The distended lateral ventricles occurred as a result of aqueduct stenosis superimposed on ciliary degeneration and destruction of ependymal cells. The brain virus titers were high on days 3, 5 and 7 but never exceeded the titer of the original dose given. Positive serum hemagglutination-inhibition titers persisted throughout the experiment.This publication has 33 references indexed in Scilit:
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