FUNGICIDAL PROPERTIES OF CERTAIN CLINICALLY RECOGNIZED FUNGICIDES

Abstract

The object of this study was the development of a formula for the local treatment of epidermophytosis based on laboratory facts. This seemed desirable for a number of reasons: the continued numerical increase of epidermophytosis; the realization by the laity of the harmful possibilities of this condition, if it is neglected, and the need for a topical medicament sufficiently fungistatic to be relied on as the sole agent in the treatment of the mildest expressions of this condition and as an adjunct in the more severe forms. It was decided to build this formula with iodine as the basis, since chemotherapeutic studies have shown iodine to be the best present-day fungicide. A liquid was believed to be superior to an ointment, principally because of the more efficient action of the iodine, since Sollmann has stated that the iodine in ointments through chemical union with the bases, is unable to react