The Toxic Effects of Phenylbutazone (Butazolidin)

Abstract

DRUGS employed in the past and at present for the relief of pain in the various forms of arthritis carry with them noxious traits that limit or prevent their use. Cincophen was abandoned because of its adverse effects on the liver. Cortisone has been responsible for serious side reactions, which have been limited by professional and public awareness of this drug's unwanted effects. Toxic reactions from gold have been held within bounds because it cannot be self-administered. Aminopyrine is no longer used because of its disastrous effects on the bone marrow. Today, phenylbutazone (Butazolidin), chemically similar to aminopyrine, is in . . .