Intracellular Site of Newcastle Disease Virus Nucleic Acid Synthesis.

Abstract

Summary Under conditions in which cellular RNA synthesis was inhibited by actinomycin D, incorporation of C¹⁴-uridine took place into RNA of NDV-infected cells and was measured by scintillation counting. In autoradiograph experiments employing H³-uridine, synthesis of NDV-RNA was demonstrated to take place in the cytoplasm of infected cells.