Predictive testing for Huntington disease: I. Description of a pilot project in British Columbia
- 1 February 1989
- journal article
- research article
- Published by Wiley in American Journal of Medical Genetics
- Vol. 32 (2), 211-216
- https://doi.org/10.1002/ajmg.1320320214
Abstract
The discovery of DNA markers linked to the gene causing Huntington disease (HD) has allowed the development of predictive testing programs for persons at‐risk. A pilot program was established in British Columbia in November 1986. Ninetyfive persons are currently enrolled. The major objective of this project is to introduce and evaluate a protocol for the delivery of test results to persons at‐risk for HD. The criteria for entry and details of the psychosocial assessment before and after receiving a modified risk are presented. The guidelines that are developed from this project will have major applications for predictive testing programs for other late onset autosomal dominant disorders.Keywords
This publication has 23 references indexed in Scilit:
- Predictive testing for Huntington disease: II. Demographic characteristics, life‐style patterns, attitudes, and psychosocial assessments of the first fifty‐one test candidatesAmerican Journal of Medical Genetics, 1989
- Preclinical testing in Huntington diseaseAmerican Journal of Medical Genetics, 1987
- Attitudes toward presymptomatic testing in Huntington diseaseAmerican Journal of Medical Genetics, 1987
- Intended use of predictive testing by those at risk for Huntington diseaseAmerican Journal of Medical Genetics, 1987
- Attitudes of persons at risk for Huntington disease toward predictive testingAmerican Journal of Medical Genetics, 1987
- Suicide and attempted suicide in Huntington disease: Implications for preclinical testing of persons at riskAmerican Journal of Medical Genetics, 1986
- Potential impact of a predictive test on the gene frequency of Huntington diseaseAmerican Journal of Medical Genetics, 1984
- Attitudes of subjects at risk and their relatives towards genetic counselling in Huntington's chorea.Journal of Medical Genetics, 1983
- The measurement of pessimism: The Hopelessness Scale.Journal of Consulting and Clinical Psychology, 1974
- Socio-Psychiatric Consequences of Huntington's DiseaseThe British Journal of Psychiatry, 1970