Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics
- 21 May 2008
- Vol. 377 (1), 170-183
- https://doi.org/10.1016/j.virol.2008.04.005
Abstract
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This publication has 113 references indexed in Scilit:
- Potent D-peptide inhibitors of HIV-1 entryProceedings of the National Academy of Sciences, 2007
- Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligandsVirology, 2007
- Immunogenicity of recombinant human immunodeficiency virus type 1-like particles expressing gp41 derivatives in a pre-fusion stateVaccine, 2007
- A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120Virology, 2007
- Structural definition of a conserved neutralization epitope on HIV-1 gp120Nature, 2007
- Cross-reactive HIV-1 neutralizing monoclonal antibodies selected by screening of an immune human phage library against an envelope glycoprotein (gp140) isolated from a patient (R2) with broadly HIV-1 neutralizing antibodiesVirology, 2007
- Selection of a novel gp41-specific HIV-1 neutralizing human antibody by competitive antigen panningJournal of Immunological Methods, 2006
- Increased efficacy of HIV-1 neutralization by antibodies at low CCR5 surface concentrationBiochemical and Biophysical Research Communications, 2006
- Structural basis for HIV-1 neutralization by a gp41 fusion intermediate–directed antibodyNature Structural & Molecular Biology, 2006
- Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection.Proceedings of the National Academy of Sciences, 1994