S-norfluoxetine microinfused into the basolateral amygdala increases allopregnanolone levels and reduces aggression in socially isolated mice
- 30 June 2011
- journal article
- Published by Elsevier in Neuropharmacology
- Vol. 60 (7-8), 1154-1159
- https://doi.org/10.1016/j.neuropharm.2010.10.011
Abstract
No abstract availableKeywords
Funding Information
- National Institute of Mental Health (MH 085999)
This publication has 65 references indexed in Scilit:
- In a mouse model relevant for post-traumatic stress disorder, selective brain steroidogenic stimulants (SBSS) improve behavioral deficits by normalizing allopregnanolone biosynthesisBehavioural Pharmacology, 2010
- Behavioral and Neural Analysis of GABA in the Acquisition, Consolidation, Reconsolidation, and Extinction of Fear MemoryNeuropsychopharmacology, 2010
- Neurosteroids’ effects and mechanisms for social, cognitive, emotional, and physical functionsPsychoneuroendocrinology, 2009
- SSRIs act as selective brain steroidogenic stimulants (SBSSs) at low doses that are inactive on 5-HT reuptakeCurrent Opinion in Pharmacology, 2009
- Decreased corticolimbic allopregnanolone expression during social isolation enhances contextual fear: A model relevant for posttraumatic stress disorderProceedings of the National Academy of Sciences, 2008
- Infusions of 3α,5α-THP to the VTA enhance exploratory, anti-anxiety, social, and sexual behavior and increase levels of 3α,5α-THP in midbrain, hippocampus, diencephalon, and cortex of female ratsBehavioural Brain Research, 2008
- Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in miceProceedings of the National Academy of Sciences, 2007
- The Role of the Medial Prefrontal Cortex-Amygdala Circuit in Stress Effects on the Extinction of FearNeural Plasticity, 2007
- Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesisProceedings of the National Academy of Sciences, 2006
- Fluoxetine and norfluoxetine stereospecifically and selectively increase brain neurosteroid content at doses that are inactive on 5-HT reuptakePsychopharmacology, 2006