Alterations in Kidney Weight Produced by Escherichia coli Endotoxin
- 1 May 1957
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 189 (2), 329-330
- https://doi.org/10.1152/ajplegacy.1957.189.2.329
Abstract
The rapid injection of E. coli endotoxin in eviscerated anesthetized dogs resulted in a sudden fall in kidney weight beginning within 15–35 seconds after injection and reaching a minimum weight within 10–20 minutes. This decrease in weight occurred independently from blood pressure changes and represented an average loss in weight of 25%. The results suggest that E. coli endotoxin either has a direct action on the renal vasculature or that it causes the liberation of an unknown substance, or substances, elsewhere in the body which act on the kidney.Keywords
This publication has 4 references indexed in Scilit:
- STUDIES ON THE CIRCULATORY CHANGES IN THE DOG PRODUCED BY ENDOTOXIN FROM GRAM-NEGATIVE MICROORGANISMSJCI Insight, 1956
- Hypotension (Shock) in Dogs Produced by Escherichia coli EndotoxinCirculation Research, 1956
- Canine Intestinal and Liver Weight Changes Induced by E. colt EndotoxinExperimental Biology and Medicine, 1956
- SHOCK-LIKE STATE DUE TO TRANSFUSION OF BLOOD CONTAMINATED WITH GRAM-NEGATIVE BACILLIA.M.A. Archives of Internal Medicine, 1953