Fission products and the dairy cow IV. The metabolism of 131I following single and multiple doses

Abstract

1. The change in concentration of ¹³¹I with time in plasma, urine, milk and the thyroid gland has been followed in four cows after administration of either a single oral dose or of ¹³¹I from a decaying source every 6 hr. for 14 days.2. The observed changes in concentration following multiple doses have been compared with those predicted from the single-dose experiments.3. Small discrepancies were observed between the observed and predicted course of events in urine, milk and the thyroid gland: their significance is considered to be doubtful.