Influence of Hypophysectomy on Porphyrin Synthesizing Enzyme Activity of Rat Harderian Glands and Livers.

Abstract
A study was made of porphyrin-producing enzyme activities of Harderian glands and livers of normal and hypophysectomized albino rats. Extract of Harderian glands of normal and hypophysectomized rats showed approximately equal amounts of porphyrin-producing enzyme activity. Extracts of livers of hypophysectomized animals exhibited approximately twice as much porphyrin-producing enzyme activity as extracts of liver of normal animals. Extracts of liver from hypophysectomized rats also showed greater activity than extracts of Harderian glands.