REM sleep burst neurons, PGO waves, and eye movement information
- 1 October 1983
- journal article
- research article
- Published by American Physiological Society in Journal of Neurophysiology
- Vol. 50 (4), 784-797
- https://doi.org/10.1152/jn.1983.50.4.784
Abstract
Pontogeniculooccipital (PGO) waves appeared almost simultaneously in both lateral geniculate nuclei (LGB), but in each case on had a larger amplitude and preceded the other by a few milliseconds. The larger, earlier wave is called the primary wave. Primary waves were found to appear with equal frequency in each LGB. During rapid eye movement sleep (REM sleep), LGB primary waves were ipsilateral to the direction of rapid eye movements. During REM sleep a group of cat midbrain neurons, which we call PGO burst cells, fired in stereotyped bursts at fixed latencies before ipsilateral primary waves, but they almost never fired bursts when the primary waves were contralateral. PGO burst neuron discharge also correlated with the direction of rapid eye movements during REM sleep. In wakefulness, PGO burst cells fired single spikes, not bursts, which had some correlation with LGB waves when averaged by computer. The results suggest that PGO burst cells are output elements in the PGO wave-generation system ad that PGO waves convey eye movement information to the sensory visual system in REM sleep. They also may have a role in the production of saccade-related waves in the visual system during wakefulness.This publication has 11 references indexed in Scilit:
- Functional distinction of perigeniculate and thalamic reticular neurons in the catExperimental Brain Research, 1982
- Projection of brain stem neurons to the perigeniculate nucleus and the lateral geniculate nucleus in the catBrain Research, 1982
- Efferent connections of the parabrachial nucleus in the ratBrain Research, 1980
- Ponto-Geniculo-Occipital (PGO) Burst Neurons: Correlative Evidence for Neuronal Generators of PGO WavesScience, 1978
- A new vestibular thalamic area: Electrophysiological study of the thalamic reticular nucleus and of the ventral lateral geniculate complex of the catExperimental Brain Research, 1978
- Discharge patterns of the nucleus parabrachialis lateralis neurons of the cat during sleep and wakingBrain Research, 1977
- Visual and presaccadic neuronal activity in thalamic internal medullary lamina of cat: a study of targetingJournal of Neurophysiology, 1977
- Method for reliably recording geniculate spikes during paradoxical sleep in the catBrain Research Bulletin, 1976
- Effects of ponto-mesencephalic lesions and electrical stimulation upon PGO waves and EMPs in unanesthetized catsElectroencephalography and Clinical Neurophysiology, 1976
- The effect of reticular stimulation on spontaneous and evoked activity in the cat visual cortexBrain Research, 1976