Follow-up at 4½ Years on Homosexual Men with Generalized Lymphadenopathy

Abstract
To the Editor: A longitudinal study of homosexual and bisexual men with persistent generalized lymphadenopathy was initiated in February 1981. After 30 months, 8 of 42 men (19 per cent) had the acquired immunodeficiency syndrome (AIDS), as previously reported.1 We now report our experience after 4 1/2 years: 12 of 42 patients (29 per cent) have had progression to AIDS — 7 with Kaposi's sarcoma, 2 with Pneumocystis carinii pneumonia, 1 with both these symptoms, and 1 with non-Hodgkin lymphoma. The mean duration of lymphadenopathy before diagnosis of AIDS was 25 months; before diagnosis of Kaposi's sarcoma, 19 months; before . . .