A CHARACTERISTIC CELL IN NASAL SECRETIONS DURING PRODROMAL MEASLES

Abstract
The multinucleate giant cell of lymphoid tissue known by the forbidding eponym of Warthin-Finkeldey cell is a well-known finding in prodromal measles. Pathologists occasionally find and prophetically report on these cells seen in an appendix or tonsil. Less well known are the epithelial giant cells of the bronchial mucosa. Good illustrations of these can be seen in the studies of Denton, Semsroth, Corbett, Pinkerton and co-workers, and Milles. A patient with a fatal case studied a few years ago had an abundance of such epithelial giant cells in bronchial mucosa. In the bronchial lumen, shed forms were abundant. It seemed likely, therefore, that sputum might contain the cells in recognizable form in prodromal measles. This was confirmed during our last "measles year" in a specimen taken some 48 hours before exanthem in a living patient. In the process of gathering the specimen, it became evident that children, though they coughed