GLUCOSE-6-PHOSPHATE DEHYDROGENASE-DEFICIENCY AND INCIDENCE OF HEMATOLOGIC MALIGNANCY
- 1 March 1988
- journal article
- research article
- Vol. 42 (3), 516-520
Abstract
We have evaluated the hypothesis of a negative association between glucose-6-phosphate dehydrogenase (G6PD) deficiency and cancer in a cohort of 481 Sardinian males with hematological malignancies. The frequency of G6PD deficiency in the patients was not different from the incidence in a group of 16,219 controls. The same conclusion resulted from the comparison of the frequency of expression of the GdB gene in 23 heterozygous women having a clonal hematologic disease and a control group of 37 healthy heterozygotes. Therefore at present there is no evidence that G6PD deficiency had a protective effect against development of hematologic neoplasms.This publication has 12 references indexed in Scilit:
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