Neurovirulence and induction of hydrocephalus with parental, mutant, and revertant strains of measles virus

Abstract
The relationship between neurovirulence and induction of hydrocephalus was investigated for a measles virus temperature-sensitive mutant and its revertant. The revertant regained the neurovirulence of the parental strain. At appropriate doses the parental, mutant, and revertant strains induced hydrocephalus.