Lipoproteins Quantitated by Paper Electrophoresis as an Index of Atherosclerosis

Abstract

Data dealing with cholesterol, phospholipid, their ratios, and total lipids in a group of 40 "normal" and 40 individuals with manifest coronary artery disease have been evaluated and have been found to have a low order of significance in determining the atherosclerotic status for both individuals and for groups. Serum lipoproteins separated by paper electrophoresis and visualized with Fat Red 7B have been shown to occur in 5 fractions. Of these, lipalbumin and beta lipoproteins as well as beta/alpha and beta/lipalbumin ratios reveal a high level of significance for distinguishing normal from abnormal individuals and groups.