Drugs Five Years Later
- 1 May 1982
- journal article
- research article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 96 (5), 619-625
- https://doi.org/10.7326/0003-4819-96-5-619
Abstract
Control of Paget''s disease of bone through treatment with agents that decrease bone resorption, calcitonins, diphosphonates and mithramycin, was studied. The pagetic lesion is not cured. Etidronate disodium is one of the diphosphonates. The clinical improvement attained with this drug has to be set against adverse effects, of which pain is probably the most bothersome in practice. Clinical remission can last as long as 2 yr after treatment is stopped.Keywords
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