A Clinical Strain ofEscherichia coliPossessing CMY-2 Plasmid-Mediated Amp Cβ-Lactamase: An Emerging Concern in Pediatrics?
- 1 December 2002
- journal article
- case report
- Published by Mary Ann Liebert Inc in Microbial Drug Resistance
- Vol. 8 (4), 329-333
- https://doi.org/10.1089/10766290260469598
Abstract
A 5-year-old child was colonized by an isolate of Escherichia coli that transferred resistance to third-generation cephalosporins and cefoxitin. This resistance phenotype was encoded on a >75-kb plasmid pLRM 22. The transferable plasmid contained both blaCMY-2 and blaTEM-1b. Increasing reports of CMY-2 beta-lactamase in clinical isolates in children raise concerns about the empiric use of third-generation cephalosporins in this patient group.Keywords
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