The changes in the plasma and cells during experimental human salt deficiency

Abstract
During exptl salt deficiency induced by diet and sweating, the serum Na and Cl fell. The serum proteins, the Hb. and cell vols. rose, in spite of a liberal fluid intake. The red blood cells did not alter in size, and osmotic equilibrium with the hypotonic plasma appeared to be maintained by passage of K and Cl out of the cells. After restoration of a free NaCl intake the serum proteins, Hb. and cell vol. fell temporarily below their initial levels.