ACYCLOVIR AND IDOXIURIDINE TREATMENT OF HERPES SIMPLEX KERATITIS — A DOUBLE BLIND CLINICAL STUDY
- 1 October 1982
- journal article
- research article
- Published by Wiley in Acta Ophthalmologica
- Vol. 60 (5), 838-844
- https://doi.org/10.1111/j.1755-3768.1982.tb06748.x
Abstract
Patients (35) with herpes simplex keratitis were treated in a double-blind clinical trial. Patients (18) (10 with pure epithelial and 8 with accompanying stromal affection) were treated with 3% acyclovir (ACV) eye ointment, and 20 patients (10 with pure epithelial and 10 with accompanying stromal affection) were treated with 0.5% of idoxuridine (IDU). The cure rate was 94% in the ACV group compared to 70% in the IDU group. This was significantly higher in the ACV group. Only minor adverse reactions were recorded.Keywords
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