Constituents of Cnidium officinale MAKINO. Structure of Senkyunolide and Gas Chromatography-Mass Spectrometory of the Related Phthalides
Open Access
- 1 January 1977
- journal article
- research article
- Published by Pharmaceutical Society of Japan in YAKUGAKU ZASSHI
- Vol. 97 (3), 237-243
- https://doi.org/10.1248/yakushi1947.97.3_237
Abstract
From the ether extract of C. officinale (Umbelliferae; Japanese name Senkyu), 6 phthalides were isolated by column and preparative TLC. One of them was a new phthalide and named senkyunolide. The structure of senkyunolide was determined by correlation with the known butylphthalide as (3S)-3-butyl-4,5-dihydrophthalide. Mass spectroscopy was the most satisfactory method for structural analysis of phthalides and showed a definite systematic fragmentation starting from the cleavages at the allylic position.Keywords
This publication has 1 reference indexed in Scilit:
- Studies on the constituents of umbelliferae plants—IXTetrahedron, 1964