Distribution of S1-nuclease Sensitive Sites and Double-strand Breaks in γ-irradiated λ-DNA
- 1 January 1984
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 46 (6), 675-679
- https://doi.org/10.1080/09553008414551911
Abstract
Double-strand breaks and regions with unpaired bases (S1-nuclease sensitive sites) are formed in the DNA of .gamma.-irradiated .lambda.-phages. The frequency of both events was determined in the various fragments produced after digestion with a restriction enzyme (Eco RI). Both types of radiation damage evidently are randomly distributed in the DNA molecule. There is no hint that the S1 sites are formed in preferred regions of the .lambda.-genome.This publication has 9 references indexed in Scilit:
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