That psychoses may occur as a symptom of bromide intoxication has been known for many years, but only since 1925, when Hauptmann described a modification of Walter's1 method for determining the concentration of bromides in the serum, has it been possible to diagnose them with ease. Before 1925 bromide psychoses doubtless were overlooked as frequently as syphilis in the days before the Wassermann test. In spite of the help given by the Walter-Hauptmann test, the recognition of a bromide psychosis is not always a simple matter. The difficulty is very much like that sometimes encountered in cases of syphilis. A