THE PROLIFERATIVE AND ANAMNESTIC ANTIBODY RESPONSE OF RABBIT LYMPHOID CELLS IN VITRO
Open Access
- 1 August 1969
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 130 (2), 287-297
- https://doi.org/10.1084/jem.130.2.287
Abstract
Popliteal lymph nodes were obtained from rabbits 4 days to 9 months after a primary injection of diphtheria toxoid or bovine γ-globulin into the footpad. The ability of cells from these nodes to proliferate upon reexposure to antigen in vitro was compared to the height of the secondary response produced by tissue fragments. In addition, a comparison was made between the responsiveness of draining and contralateral lymph nodes.Keywords
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