Cytopathogenic Effects in a Cell Culture Infected with a Murine Leukemia Virus.
- 1 May 1965
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 119 (1), 186-189
- https://doi.org/10.3181/00379727-119-30132
Abstract
Summary Cell cultures grown in modified NCTC 109 medium and infected with the Rauscher leukemia virus showed CPE when subcultured in Eagle's basal medium. Non-infected control cultures treated in a similar manner showed no CPE. The CPE in infected cultures included increased cytoplasmic eosin-ophilia in the form of either eosinophilic granules or inclusion bodies, cytoplasmic vacuolization, and marked variation in the size, shape, and intensity of staining of cell nuclei.Keywords
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